Circulating microRNAs and prediction of asthma exacerbation in childhood asthma
نویسندگان
چکیده
منابع مشابه
micrornas and asthma regulation.
micrornas participate in the regulation of asthma, the goal of this study is to summarize recent researches on the roles of micrornas in the pathogenesis of asthma. a review of the english medical literatures was conducted by searching pubmed for studies concerning asthma and micrornas. the results of the present study indicate that micrornas play important roles in regulating asthma immune res...
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INTRODUCTION Circulating microRNAs (miRNA) are promising biomarkers for human diseases. Our study hypothesizes that circulating miRNA would reveal candidate biomarkers related to airway hyperresponsiveness (AHR) and provide biologic insights into asthma epigenetic influences. METHODS Serum samples obtained at randomization for 160 children in the Childhood Asthma Management Program were profi...
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Background: Asthma is the chronic inflammation of airways characterized by eosinophilic infiltration, mucus overproduction, airway hyper-responsiveness and airway remodeling. These changes are induced mostly by cytokines which are produced by T helper (Th) 2 cells. Recently, the role of interleukin-23 (IL-23) in the pathogenesis of adultallergic asthma has been studied. Objective: To explore IL...
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Patients allergic to aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) who develop respiratory reactions such as bronchospasm or asthma exacerbation have aspirin-induced asthma or NSAIDs-exacerbated respiratory disease. However, large-scale studies have not been conducted to investigate the risk of aspirin/NSAIDs exposure in children with asthma. Therefore, this study evaluated the relat...
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Questionnaires and twice daily peak expiratory flow measurements were used to evaluate the effects of the menstrual cycle in asthmatic women. Forty per cent of women reported premenstrual deterioration in their symptoms and this was confirmed by peak flow recordings. No correlations were found between premenstrual exacerbation of asthma and symptoms of premenstrual tension, consumption of aspir...
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ژورنال
عنوان ژورنال: Respiratory Research
سال: 2018
ISSN: 1465-993X
DOI: 10.1186/s12931-018-0828-6